Should the wound be closed with absorbable or non-absorbable sutures after surgery for Dupuytrens Contracture

ISRCTN	ISRCTN85526661
DOI	https://doi.org/10.1186/ISRCTN85526661
Protocol serial number	N0280141212
Sponsor	Department of Health
Funders	Wirral Hospitals NHS Trust (UK), NHS R&D Support Funding

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Ms Kim Howard
Scientific

Fracture and Orthopedic Clinic
Wirral Hospital NHS Trust
Arrowe Park Road
Upton
Wirral
CH49 5PE
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Would surgical treatment of Dupuytren's Contracture involves less discomfort for patients if absorbable (dissolving) sutures were used instead of non-absorbable sutures? Would absorbable sutures significantly reduce the amount of time nursing staff need to allocate to the care of patients having surgery for Dupuytrens Contracture?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Musculoskeletal Diseases: Dupuytren's disease
Intervention	Randomised controlled trial: 1. absorbable-vicryl rapide 5/0 sutures 2. non-absorbable-prolene 5/0 sutures
Intervention type	Other
Primary outcome measure(s)	Patients discomfort/pain will be measured using visual analogue and non-parametric Mann Whitney test. The difference in the mean time the nurses spend with the patients in the two groups will be investigated using an independent t-test. Healing complications will probably take form of grouped data and comparisons of the two groups will be dome by chi-squared test.
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/05/2005

Participant type(s)	Patient
Age group	Adult
Sex	All
Target sample size at registration	60
Key inclusion criteria	All patients that are listed for fasciectomy for Dupuytren's Contracture.
Key exclusion criteria	1. Fasciectomy with skin grafting 2. Fasciectomy for recurrent diseases at the site of previous surgery
Date of first enrolment	01/05/2004
Date of final enrolment	31/05/2005

Fracture and Orthopedic Clinic

Wirral
CH49 5PE
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/10/2009		Yes	No