The effect of prostanoid precursors on platelet angiotensin II binding
| ISRCTN | ISRCTN85634342 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN85634342 |
| Protocol serial number | N0158024607 |
| Sponsor | Department of Health (UK) |
| Funder | North Staffordshire Research and Development Consortium (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 15/01/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr PMS O'Brien
Scientific
Scientific
Obstetrics and Gynaecology Academic Department
Maternity Block
City General
Newcastle Road
Stoke-on-Trent
ST4 6QG
United Kingdom
| Phone | +44 (0)1782 554998 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | To determine the effect of fish oil dietary supplements and aspirin on platelet angiotensin II binding. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Hypertension |
| Intervention | Normotensive and hypertensive women will be randomly allocated in a double blind manner to one of the four groups: fish oil, aspirin, fish oil and aspirin and placebo. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | fish oil, aspirin |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Target sample size at registration | 128 |
| Key inclusion criteria | 128 women in total will be recruited, 32 patients to each of the four treatment arms. Half the women will be hypertensive and the other half normotensive. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/1994 |
| Date of final enrolment | 01/06/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Obstetrics and Gynaecology Academic Department
Stoke-on-Trent
ST4 6QG
United Kingdom
ST4 6QG
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/01/1999 | Yes | No |
