Taurolidine-citrate vs heparin as catheter lock solutions in paediatric patients

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Prof Uwe Querfeld
Scientific

Department of Pediatric Nephrology
Charité Universitätsmedizin Berlin
Berlin
13353
Germany

Primary study design	Interventional
Study design	Randomized prospective study in pediatric hospital with stratification for patients treated in renal/oncology/hematology departments
Secondary study design	Randomised controlled trial
Scientific title
Study acronym	Taurolock study
Study objectives	Use of taurolidine-citrate for catheter locking leads to a significant reduction of bacterial growth and catheter-related infections in paediatric patients with implanted central venous catheters
Ethics approval(s)	Approval received by local ethics committee (Ethikkommission 2 am Campus Virchow Klinikum) on 29 September 2006 (ref: EA2/084/06).
Health condition(s) or problem(s) studied	Catheter-related infections
Intervention	Taurolidine-citrate vs heparin as catheter lock solutions
Intervention type	Other
Primary outcome measure(s)	Bacterial growth/biofilm formation in removed catheters
Key secondary outcome measure(s)	Catheter-related infections, catheter occlusions
Completion date	31/12/2007

Participant type(s)	Patient
Age group	Child
Sex	Not Specified
Target sample size at registration	100
Key inclusion criteria	Paediatric patients with newly implanted central venous catheters
Key exclusion criteria	Bacteremia/sepsis ongoing; allergy against heparin or taurolidine
Date of first enrolment	01/01/2007
Date of final enrolment	31/12/2007

Department of Pediatric Nephrology

Berlin
13353
Germany

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan