Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF)

ISRCTN	ISRCTN86892369
DOI	https://doi.org/10.1186/ISRCTN86892369
Secondary identifying numbers	N0059122213

Submission date: 12/09/2003
Registration date: 12/09/2003
Last edited: 31/10/2019

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Pregnancy and Childbirth

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Karen Martin
Scientific

University of Sheffield
OGN & Midwifery
Level 4
Jessop Wing
Sheffield
S10 2SF
United Kingdom

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Other
Participant information sheet	Not available in web format, please use the contact details below to request a patient information sheet
Scientific title	Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF)
Study objectives	Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF). The success rates of human in vitro fertilisation remain disappointingly low, only 25% of couples will take home a baby (HFEA report 1999.) The quality of eggs collected from a woman's ovaries has a significant influence on the implantation potential of any resulting embryos and therefore the chances of a patient becoming pregnant. The aims of this study are: a. To determine whether the medium used to flush ovarian follicles during egg collection in IVF has an impact on oocyte quality, fertilisation rates and subsequent embryo development b. To compare the use of a new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Pregnancy and Childbirth: In vitro fertilisation (IVF)
Intervention	Compare the use of new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).
Intervention type	Other
Primary outcome measure	Currently unavailable.
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/10/2002
Completion date	01/09/2003

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	Female
Target number of participants	Not provided at time of registration
Key inclusion criteria	Female patients, Assisted Conception Unit.
Key exclusion criteria	Does not meet inclusion criteria
Date of first enrolment	01/10/2002
Date of final enrolment	01/09/2003

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

University of Sheffield

Sheffield
S10 2SF
United Kingdom

Sponsor information

Department of Health (UK)
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.doh.gov.uk

Funders

Funder type

Hospital/treatment centre

Sheffield Teaching Hospitals NHS Foundation Trust (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Abstract results	results presented at the Association of Clinical Embryologists Annual Meeting	01/01/2009	31/10/2019	No	No

Editorial Notes

31/10/2019: Publication reference added.
13/10/2017: No publications found, study status unverified