Circuit Weight Training to lower Blood Pressure in Obese individuals with Resistant Hypertension
| ISRCTN | ISRCTN87889245 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN87889245 |
| Protocol serial number | RF-06-0419 |
| Sponsor | University of Alberta (Canada) |
| Funder | University of Alberta Hospital Foundation (Canada) (ref: RF-06-0419) |
- Submission date
- 20/05/2006
- Registration date
- 16/10/2006
- Last edited
- 13/12/2007
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Raj Padwal
Scientific
Scientific
Clinical Pharmacology and Internal Medicine
University of Alberta
2E3.22 Walter C. Mackenzie Health Sciences Center
8440 - 112 Street
Edmonton
Alberta
T6G 2B7
Canada
| Phone | +1 780 407 8153 |
|---|---|
| rpadwal@ualberta.ca |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | CT, ORH & BP |
| Study objectives | In comparison with the Usual Care group (UC), obese hypertensive individuals undergoing 12 weeks of Circuit Weight Training (CWT), will exhibit greater reductions in blood pressure. |
| Ethics approval(s) | University of Alberta Health Research Ethics Board (HREB) (ref no: 6276). |
| Health condition(s) or problem(s) studied | Obesity and /or resistant hypertension |
| Intervention | Circuit Weight Training (CWT) group: Individuals will be prescribed an exercise regimen based on baseline fitness and strength assessments and their exercise blood pressure response. Loads prescribed will be low resistance but high volume (two to three sets of 15 repetitions). Subjects will be asked to train on at least three non-consecutive days of the week and given free membership to local health club facilities for the duration of the intervention (12 weeks). Adherence to CWT intervention will be monitored via electronic attendance records at the health club facilities Usual Care (UC) Group: Individuals randomly assigned to the usual care group will be asked to continue their current level of activity for the duration of the intervention (12 weeks). Both groups will recieve the same nutritional counselling at the start of the intervention. |
| Intervention type | Other |
| Primary outcome measure(s) |
Efficacy of prescribing circuit weight training in reducing blood pressure of obese resistant hypertensives |
| Key secondary outcome measure(s) |
1. Effiacy of circuit weight training in reducing weight |
| Completion date | 01/02/2007 |
| Reason abandoned (if study stopped) | This study has been cancelled due to the private fitness centre pulling out of the trial. |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target sample size at registration | 40 |
| Key inclusion criteria | 1. Aged 25 to 70 years 2. Obese (Body Mass Index [BMI] more than 30 kg/m^2) 3. Mean 24 hour ambulatory blood pressure of 150/99 mmHg or less (on drug therapy) |
| Key exclusion criteria | 1. White-coat hypertension 2. Secondary hypertension 3. Unstable cardiovascular disease 4. Not residing in Edmonton or the surrounding area |
| Date of first enrolment | 01/06/2006 |
| Date of final enrolment | 01/02/2007 |
Locations
Countries of recruitment
- Canada
Study participating centre
Clinical Pharmacology and Internal Medicine
Alberta
T6G 2B7
Canada
T6G 2B7
Canada
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
