TURP and laser therapy for men presenting with lower urinary tract symptoms (LUTS) and chronic retention of urine
| ISRCTN | ISRCTN91226142 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN91226142 |
| Protocol serial number | N/A |
| Sponsor | NHS R&D Regional Programme Register - Department of Health (UK) |
| Funder | NHS Executive South West (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 14/01/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Urological and Genital Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Jenny Donovan
Scientific
Scientific
University of Bristol
Department of Social Medicine
Canynge Hall
Whiteladies Road
Bristol
BS8 2PR
United Kingdom
| Phone | +44 (0)117 928 7214 |
|---|---|
| jenny.donovan@bristol.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | The CLasP Study |
| Study objectives | We assessed the effectiveness of laser therapy versus transurethral prostatic resection in men with symptomatic chronic urinary retention secondary to benign prostatic enlargement. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Urological and genital diseases: Lower urinary tract symptoms |
| Intervention | 1. Laser therapy involved neodymium:YAG noncontact visual prostate ablation 2. Transurethral prostatic resection (TURP) was performed by standard electroresection |
| Intervention type | Other |
| Primary outcome measure(s) |
I-PSS quality of life score, maximum urinary flow and post-void residual urine volume. |
| Key secondary outcome measure(s) |
Treatment failure, complications, hospital stay and catheterization time. |
| Completion date | 30/05/1998 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Male |
| Target sample size at registration | 82 |
| Key inclusion criteria | Patients reporting moderate to severe lower urinary tract symptoms with an International Prostate Symptom Score (I-PSS) of 8 or more, benign prostatic enlargement and a persistent post-void residual urine volume of more than 300 ml. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/10/1994 |
| Date of final enrolment | 30/05/1998 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University of Bristol
Bristol
BS8 2PR
United Kingdom
BS8 2PR
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/07/2000 | Yes | No |
