A multidisciplinary study of the management of neuroleptic medication in schizophrenia: Educational and collaborative approaches
| ISRCTN | ISRCTN93636537 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN93636537 |
| Protocol serial number | G9322371 |
| Sponsor | Medical Research Council (MRC) (UK) |
| Funder | Medical Research Council (MRC) (UK) |
- Submission date
- 23/10/2000
- Registration date
- 23/10/2000
- Last edited
- 19/02/2020
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Richard Bentall
Scientific
Scientific
Psychology Department
University of Manchester
Coupland 1 Building
Oxford Road
Manchester
M13 9PL
United Kingdom
| abc@email.com |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | A multidisciplinary study of the management of neuroleptic medication in schizophrenia: Educational and collaborative approaches |
| Study objectives | 1. To investigate the determinants of psychotic patients' adherence to prescribed neuroleptic medication 2. To compare two different approaches to enhancing patients' adherence to prescribed neuroleptic medication |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Schizophrenia |
| Intervention | 1. Compliance intervention (patients educated about benefits of neuroleptic medication) 2. Alliance intervention (structured intervention in which patients are encouraged to rationally appraise the costs and benefits of their neuroleptic medication) 3. Treatment as usual |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Neuroleptics |
| Primary outcome measure(s) |
1. Attitudes towards neuroleptic medication as measured by the Drug Attitudes Inventory |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/2000 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 228 |
| Total final enrolment | 228 |
| Key inclusion criteria | Patients suffering from Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV) schizophrenia or schizoaffective disorder admitted to acute psychiatric wards in the North West of England and North Wales. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/1995 |
| Date of final enrolment | 01/06/2000 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Psychology Department
Manchester
M13 9PL
United Kingdom
M13 9PL
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/11/1998 | Yes | No | |
| Results article | results | 01/02/2003 | Yes | No | |
| Results article | results | 01/11/2003 | Yes | No | |
| Results article | results | 01/12/2003 | Yes | No | |
| Results article | results | 01/07/2005 | Yes | No | |
| Results article | results | 01/07/2005 | 19/02/2020 | Yes | No |
Editorial Notes
19/02/2020: The following changes have been made:
1. Publication reference added.
2. The final enrolment number has been added from the reference.
