Collaborative Care: Depression Initative in the Medical setting
| ISRCTN | ISRCTN95575369 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN95575369 |
| Secondary identifying numbers | NL805 (NTR818) |
- Submission date
- 01/12/2006
- Registration date
- 01/12/2006
- Last edited
- 20/08/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English Summary
Not provided at time of registration
Contact information
Dr Eva Horn
Scientific
Scientific
Trimbos-instituut/Netherlands institute of Mental Health and Addiction
Da Costakade 45
P.O. Box 725
Utrecht
3500 AS
Netherlands
| Phone | +31 (0)30 2959303 |
|---|---|
| ehorn@trimbos.nl |
Study information
| Study design | Randomised controlled parallel armed trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | Cost-effectiveness of collaborative care for chronic medically ill patients with comorbid depressive disorder in the general hospital setting. |
| Study acronym | CC:DIM |
| Study hypothesis | The collaborative care approach is expected to be more effective and more cost-effective compared to care as usual. |
| Ethics approval(s) | The local ethics board of the 'Onze Lieve Vrouwe Gasthuis' (Amsterdam, the Netherlands) is in charge of approval of this study, and ethics approval was approved on the 21st December 2006. |
| Condition | Chronic medically ill, Comorbid depressive disorder |
| Intervention | A treatment of depression fit in the collaborative care model with problem solving treatment, an antidepressant algorithm, contracting, care management, and a manual guided self-help depression for chronically ill patients. |
| Intervention type | Other |
| Primary outcome measure | Severity of depressive symptoms. |
| Secondary outcome measures | The cost-utility of collaborative care compared to CAU. |
| Overall study start date | 01/12/2006 |
| Overall study end date | 01/12/2010 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 126 |
| Participant inclusion criteria | 1. All patients of the Onze Lieve Vrouwe Gasthuis (OLVG) visiting the participating outpatient clinics: a. diabetes b. cardiology c. Human Immumodeficiency Virus (HIV) d. part of lung medicine (patients with Chronic Obstructive Pulmonary Disease [COPD]) and who already have a diagnosis specified in their file 2. Patients are included in the study if a cut off score of 15 (moderate to severe depressive disorder) is reached on a the Patient Health Questionnaire (PHQ-9), which measures depression severity 3. The symptoms have to be present for at least six weeks or have to cause marked dysfunctioning (e.g. problems at work, housekeeping) |
| Participant exclusion criteria | 1. Suicidality (in case of a high risk for suicide, patients will be referred) 2. Concerning the following criteria a suggestion is given to the patients concerned a different kind of help: a. psychotic b. suffering from dementia or delirium c. insufficient knowledge of the Dutch language to fill in questionnaires d. serious mental impairment e. alcohol or drug addiction f. already receiving psychiatric treatment g. pregnancy h. bipolar disorder 3. Concerning HIV patients: a. organic psychosyndrome b. personality change c. in terminal phase |
| Recruitment start date | 01/12/2006 |
| Recruitment end date | 01/12/2010 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Trimbos-instituut/Netherlands institute of Mental Health and Addiction
Utrecht
3500 AS
Netherlands
3500 AS
Netherlands
Sponsor information
Trimbos-institute/Netherlands Institute of Mental Health and Addiction (The Netherlands)
Hospital/treatment centre
Hospital/treatment centre
P.O. Box 725
Utrecht
3500 AS
Netherlands
| Phone | +31 (0)30 2971100 |
|---|---|
| info@trimbos.nl | |
| Website | http://www.trimbos.nl/default37.html |
"ROR" |
https://ror.org/02amggm23 |
Funders
Funder type
Research organisation
Foundation Reserves Voormalige Vrijwillige Ziekenfondsverzekering (RVVZ) (The Netherlands)
No information available
Onze Lieve Vrouwe Gasthuis (OLVG) (The Netherlands)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Protocol article | Protocol | 26/02/2007 | Yes | No | |
| Results article | 26/02/2007 | 20/08/2021 | Yes | No |
Editorial Notes
20/08/2021: Publication reference added.
