Do regular oral antibiotics prevent hospital admission for patients with moderate to severe chronic obstructive pulmonary disease (COPD)?
| ISRCTN | ISRCTN97227471 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN97227471 |
| Protocol serial number | N0333119989 |
| Sponsor | Department of Health (UK) |
| Funder | Hereford Hospitals NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 14/03/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Phil Ryan
Scientific
Scientific
Consultant Oncologist
The County Hospital
Union Walk
Hereford
HR1 2ER
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Blinded randomised placebo controlled intervention |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | To find out whether taking a regular oral antibiotics prevents hospital admission for patients with moderate to severe COPD? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory: Chronic obstructive pulmonary disease (COPD) |
| Intervention | Blinded randomised placebo controlled intervention study using oral antiobiotics (amoxycillin) regularly. From November 2003 to March 2004 recruiting COPD patients. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | amoxycillin |
| Primary outcome measure(s) |
Researching a clinical problem which is common and also has a large impact upon acute medical admissions |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 20/12/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Patients from medical admissions and the Out Patient Department. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 20/12/2002 |
| Date of final enrolment | 20/12/2006 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Consultant Oncologist
Hereford
HR1 2ER
United Kingdom
HR1 2ER
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
