Effectiveness of a breakthrough collaborative aimed at the implementation of depression guidelines in primary and secondary care
| ISRCTN | ISRCTN99634826 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN99634826 |
| Secondary identifying numbers | N/A |
- Submission date
- 26/02/2007
- Registration date
- 26/02/2007
- Last edited
- 09/05/2019
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Ms G Franx
Scientific
Scientific
Trimbos Institute
P.O. Box 725
Utrecht
3500 AS
Netherlands
| Phone | +31 (0)30 295 9437 |
|---|---|
| gfranx@trimbos.nl |
Study information
| Study design | The design is a quasi-experimental trial, consisting of a systematic measurement of patient outcomes (depression symptoms and functional status) and care provided by practitioners (antidepressant prescription, monitoring) of the new Depression Collaborative |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Single-centre |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | Effectiveness of a breakthrough collaborative aimed at the implementation of depression guidelines in primary and secondary care |
| Study objectives | Implementation of innovations in mental health care needs multifaceted strategies in order to improve care with better outcomes for patients. The hypothesis in this study is: teams of health care professionals participating in a Breakthrough Depression Project implement national guidelines to a higher degree with better outcomes for patients than a control group of health care professionals and their patients receiving care as usual. |
| Ethics approval(s) | Approval received from the local ethics board (METIGG-ZUID [South]) on the 18th April 2007 (ref: 6.115). |
| Health condition(s) or problem(s) studied | Implementation, depression, guidelines |
| Intervention | The intervention group receives depression care according to guidelines, the control group receives care as usual. Depression care according to guidelines concerns a series of effective interventions, in a specific order. According to this stepped care principle patients start at the lowest level of treatment from which an effect can be expected in order to step up to a more intense level of treatment, when the first step has not generated the expected effect within a number of weeks. The levels of treatment consist of one of more of the following interventions: 1. Information 2. Psycho-education 3. Individual or group self-help course 4. Running therapy 5. Problem solving treatment or brief psychotherapeutic interventions 6. Antidepressants 7. Psychotherapy (cognitive therapy, cognitive behavioural therapy, interpersonal psychotherapy) Stepped care assumes that depression symptoms are being monitored. In the intervention group a Beck Depression Inventory will be administered every six weeks until the score is under ten. |
| Intervention type | Other |
| Primary outcome measure | Outcomes are on the professional, organisational and on the patient level. 1. The primary outcome measure of professional performance is: a. a reduction of antidepressants prescription for patients with non-severe depression (reduction of overtreatment) 2. The primary outcome measure of organisational performance is: a. a reduction of the waiting time to specialised depression treatment for patients with severe or long term depression (reduction of under-treatment) 3. The primary outcome measures on the patient level are: a. a reduction in depressive symptoms and an improvement in disability status (effectiveness) |
| Secondary outcome measures | Secondary measures are: 1. Professional performance: satisfaction with collaboration, patient education delivered 2. Organisational level: monitoring system in use 3. Patient level outcomes: care consumption, satisfaction with care |
| Overall study start date | 01/09/2006 |
| Completion date | 01/03/2009 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Not Specified |
| Target number of participants | 585 |
| Total final enrolment | 536 |
| Key inclusion criteria | 1. Aged 18 to 65 2. Sufficient Dutch language skills |
| Key exclusion criteria | 1. Aged younger than 18 and older than 65 2. Insufficient Dutch langauage skills |
| Date of first enrolment | 01/09/2006 |
| Date of final enrolment | 01/03/2009 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Trimbos Institute
Utrecht
3500 AS
Netherlands
3500 AS
Netherlands
Sponsor information
Trimbos-institute - Netherlands Institute of Mental Health and Addiction (The Netherlands)
Research organisation
Research organisation
P.O. Box 725
Utrecht
3500 AS
Netherlands
| Phone | +31 (0)30 297 1100 |
|---|---|
| info@trimbos.nl | |
"ROR" |
https://ror.org/02amggm23 |
Funders
Funder type
Government
Reserve Voormalige Vrijwillige Ziekenfondsen (RVVZ) (The Netherlands) - a governmental non profit health organisation
No information available
The Netherlands Organisation for Health Research and Development (ZonMw) (The Netherlands)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 15/06/2009 | 09/05/2019 | Yes | No |
Editorial Notes
09/05/2019: Publication reference and total final enrolment added.
