The ISRCTN registry is pleased to announce a partnership with the Health Research Authority (HRA). From 1 January 2022 all CTIMPs in the UK, that are submitted to the HRA using the IRAS combined review service, will be registered on ISRCTN using data from the HRA’s systems, meaning that trialists and sponsors will not have to apply for registration separately. Please see the HRA’s guidance on research registration and our statement. If you have any queries, please contact us at

ISRCTN registry

The ISRCTN registry is a primary clinical trial registry recognised by WHO and ICMJE that accepts all clinical research studies (whether proposed, ongoing or completed), providing content validation and curation and the unique identification number necessary for publication. All study records in the database are freely accessible and searchable.

ISRCTN supports transparency in clinical research, helps reduce selective reporting of results and ensures an unbiased and complete evidence base.

ISRCTN accepts all studies involving human subjects or populations with outcome measures assessing effects on human health and well-being, including studies in healthcare, social care, education, workplace safety and economic development. The registry welcomes submissions in English from any location. Studies should ideally be registered prospectively (before recruitment starts). ISRCTN also accepts studies registered retrospectively once they are underway or after completion.

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