Online treatment of bulimia nervosa
| ISRCTN | ISRCTN06477195 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN06477195 |
| Protocol serial number | N/A |
| Sponsor | Interapy PLC (Netherlands) |
| Funders | The Dutch Innovation Fund of Collaborative Health Insurances (Innovatiefonds Zorgverzekeraars) (Netherlands) - awarded a grant to initiate the project, Interapy PLC (Netherlands) - provided consultancy, technical assistance, web-application development and application hosting support |
- Submission date
- 30/03/2010
- Registration date
- 14/04/2010
- Last edited
- 09/04/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr Bart Schrieken
Scientific
Scientific
Postbus 3884
Amsterdam
1001AR
Netherlands
| Phone | +31 (0)20 798 8300 |
|---|---|
| schrieken@interapy.nl |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Single centre randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | Online cognitive behavioural treatment of bulimia nervosa: a randomised controlled trial with a one-year follow-up |
| Study objectives | In comparison to bibliotherapy and a waitlist, online (therapist-assisted) cognitive behaviour therapy is more effective in reducing bulimic symptoms. |
| Ethics approval(s) | Study Review Board of the Department of Clinical Psychology of the University of Amsterdam approved in March 2006 |
| Health condition(s) or problem(s) studied | Bulimia nervosa |
| Intervention | The online treatment is a twenty-week program based on existing - evidence-based - treatment manuals, and incorporates cognitive behaviour therapy interventions such as psycho-education, self-monitoring, diet management, exposure, response prevention, cognitive restructuring, interventions promoting self-esteem and relapse prevention. These treatments were therapist-guided (therapist time: 7 to 14 hours). Participants in the bibliotherapy group received a hard-copy of "Overcoming bulimia and binge eating", a Dutch self-help book for BN by Johan Vanderlinden, which is based on the same cognitive-behavioral principles as applied in the online treatment. Apart from an initial introductory e-mail with instructions how to use this book, no support was provided to participants in this group. |
| Intervention type | Other |
| Primary outcome measure(s) |
Global severity of eating disorder symptoms and binging and purging frequency as measured by the Eating Disorder Examination Questionnaire (EDE-Q). Primary and secondary measures were administered at pretest, immediately after treatment (post-test), six weeks after treatment, and one year after treatment. |
| Key secondary outcome measure(s) |
Cognitive-attitudinal distortion in body experience, as measured by the Body Attitude Test (BAT). Primary and secondary measures were administered at pretest, immediately after treatment (post-test), six weeks after treatment, and one year after treatment. |
| Completion date | 01/07/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 105 |
| Total final enrolment | 105 |
| Key inclusion criteria | 1. Recurrent binging 2. Extreme weight-control behaviour (either in the form of purging as well as physical exercise) 3. Extreme concern with body shape and weight 4. Downloaded, signed, and returned an Informed Consent form 5. Aged greater than or equal to 16 years, either sex |
| Key exclusion criteria | 1. Aged less than 16 years 2. Body mass index (BMI) less than 18 kg/m^2 3. Heightened risk of dissociation or psychosis 4. Suicidal ideation indicative of plans or a history of recent suicide attempts within the past 3 years 5. Drug and alcohol abuse 6. Use of neuroleptic medication or unstable dosages of other psychiatric medication 7. Concurrent psychotherapy, or indications that another psychological disorder was prevalent Excluded respondents were referred to their GPs or to mental health centres in their vicinity. |
| Date of first enrolment | 01/07/2006 |
| Date of final enrolment | 01/07/2008 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Postbus 3884
Amsterdam
1001AR
Netherlands
1001AR
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 01/02/2012 | 09/04/2021 | Yes | No | |
| Protocol article | 01/03/2009 | Yes | No | ||
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
| Study website | Study website | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
09/04/2021: The following changes have been made:
1. Publication reference added.
2. The final enrolment number has been added from the reference.
