Stop Stroke: The South London Secondary Prevention Programme
| ISRCTN | ISRCTN10730637 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN10730637 |
| Protocol serial number | 1824/1845 |
| Sponsor | King's College London (UK) |
| Funders | The Health Foundation 1824/1845,, The Stroke Association TSA G1,, Medical Research Council Special Training Fellowship Award G106/1105, Department of Health Career Scientist Award PHCSA02/07. |
- Submission date
- 19/07/2005
- Registration date
- 07/09/2005
- Last edited
- 07/12/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Charles Wolfe
Scientific
Scientific
Division of Health & Social Care Research
King's College London
7th Floor Capital House
42 Weston Street
London
SE1 3QD
United Kingdom
| Phone | +44 (0)20 7848 6608 |
|---|---|
| charles.wolfe@kcl.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | Stop Stroke |
| Study objectives | To test the efficacy of a complex secondary prevention intervention on improving post stroke risk factor control. The study uses a cluster randomised controlled trial design with 120 general practices randomised at the start of the trial. All participants at a given practice (patients, carers and primary care staff) receive either the intervention or usual care. |
| Ethics approval(s) | Not provided at time of registration. |
| Health condition(s) or problem(s) studied | Stroke |
| Intervention | Intervention: Computer algorithms are used to systematically transform data collected by an ongoing stroke register (SLSR) into individually tailored secondary prevention plans for patients, carers and the primary care team. The plans include details of the patient's current risk factor control and evidence based advice on how to improve risk factor management. Plans are updated and distributed at three time points. Control: Usual care. |
| Intervention type | Other |
| Primary outcome measure(s) |
Prevalence of uncontrolled key modifiable risk factors for stroke (hypertension, smoking, aspirin adherence) measured at one year post stroke. |
| Key secondary outcome measure(s) |
Prevalence of other uncontrolled risk factors for stroke (cholesterol, diabetes, atrial fibrillation, obesity, heavy drinking); stroke recurrence rate. |
| Completion date | 01/01/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 450 |
| Key inclusion criteria | All patients with a diagnosis of first-in-a-lifetime stroke living in Lambeth and Southwark. |
| Key exclusion criteria | Patients must be alive six weeks post stroke, identified by the study team within six months of stroke and registered with a general practitioner. |
| Date of first enrolment | 21/07/2003 |
| Date of final enrolment | 01/01/2007 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Division of Health & Social Care Research
London
SE1 3QD
United Kingdom
SE1 3QD
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/11/2010 | Yes | No |
