Supervised high intensity continuous and interval training vs self-paced training in Chronic Obstructive Pulmonary Disease (COPD)
| ISRCTN | ISRCTN11034505 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN11034505 |
| Secondary identifying numbers | Interval training 01 |
- Submission date
- 23/02/2007
- Registration date
- 29/03/2007
- Last edited
- 22/09/2021
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Attila Somfay
Scientific
Scientific
Alkotmany u 36
Deszk
6772
Hungary
Study information
| Study design | Randomized trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | Supervised high intensity continuous and interval training vs self-paced training in Chronic Obstructive Pulmonary Disease (COPD) |
| Study acronym | INTCONT |
| Study objectives | To determine differences in responses to supervised high intensity training utilizing either continuous or interval training profiles compared to a self-paced exercise program. |
| Ethics approval(s) | The Regional Ethical Committee on Biomedical Research Involving Human Subjects at Szeged University, Faculty of Medicine and Pharmaceutics approved the study on 18 December 2006 with a reference number 134/2006. |
| Health condition(s) or problem(s) studied | Moderate to severe COPD patients |
| Intervention | Three study groups will be studied: A. Supervised, high intensity continuous training B. Supervised, interval training C. Home-based self paced training program The assignment of patients to group C will be based on the accessibility of the research center to the patients. We have to use this approach because the travel distance in the area would be unreasonable. The assignment of the subjects to the other two groups (A and B) is randomized. High intensity constant work rate (CWR) training protocol involved exercising on a cycle ergometer at a work rate equivalent to 80% peak work rate achieved on a pre-training incremental exercise test. The CWR was continued for 45 minutes per session, three sessions per week for 8-week training period. Interval training: involved a 30 min period of cycling for 2 minutes at 90% peak work rate followed by 1 minute at 50% peak work rate. This 30 min period was preceded and followed by approximately 7.5 minutes of exercise at 50% peak work rate (warm-up and cool-down phase). Home training involved cycling, stair climbing and walking in their natural environment with the same weekly periodicity and time interval as used in the in-center programs. The home training period also lasted for 8 weeks. |
| Intervention type | Other |
| Primary outcome measure | Change in peak oxygen uptake in the incremental test. |
| Secondary outcome measures | 1. After training changes in peak work rate 2. Quality of life 3. Lactate threshold 4. Changes in isotime physiologic variables (minute ventilation, ventilatory equivalents, respiratory rate and heart rate) |
| Overall study start date | 07/01/2002 |
| Completion date | 02/01/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 80 |
| Total final enrolment | 71 |
| Key inclusion criteria | 1. COPD patients 2. Forced Expiratory Volume in the first second (FEV1)<80% and FEV1/ Forced Vital Capacity (FVC)<70% |
| Key exclusion criteria | Severe cardiovascular, neurological or exercise-limiting muskuloskeletal diseases |
| Date of first enrolment | 07/01/2002 |
| Date of final enrolment | 02/01/2008 |
Locations
Countries of recruitment
- Hungary
Study participating centre
Alkotmany u 36
Deszk
6772
Hungary
6772
Hungary
Sponsor information
Department of Pulmonology, Szeged University, Faculty of Medicine and Pharmaceutics (Hungary)
University/education
University/education
Alkotmány u 36
Deszk
6772
Hungary
"ROR" |
https://ror.org/01pnej532 |
|---|
Funders
Funder type
University/education
Department of Pulmonology, Szeged University, Faculty of Medicine and Pharmeceutics (Hungary)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 01/11/2007 | 22/09/2021 | Yes | No |
Editorial Notes
22/09/2021: Publication reference added.
