Comparison of intensive and standard case management programmes for psychotic patients

ISRCTN	ISRCTN15904286
DOI	https://doi.org/10.1186/ISRCTN15904286
Secondary identifying numbers	NMH10C GE179D

Submission date: 23/01/2004
Registration date: 23/01/2004
Last edited: 20/11/2009

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Mental and Behavioural Disorders

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Francis Creed
Scientific

Department of Psychiatry
Manchester Royal Infirmary
Oxford Road
Manchester
M13 9WL
United Kingdom

Phone	+44 (0)161 276 5331
Email	Francis.Creed@man.ac.uk

Study information

Study design	Randomised controlled trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Other
Study type	Other
Scientific title
Study acronym	UK700 study
Study objectives	Case management has increasingly been the recommended approach to care for the severely mentally ill as reliance on mental hospitals has diminished. An influential series of studies in the USA suggested that intensive case management, with case loads of 1:10-15, was particularly effective with the most severe patients, reducing hospitalisation and improving aspects of outcome. Despite equivocal results from replication studies in the UK and Europe this approach is becoming accepted policy. In this study we carried out a large multicentre investigation which was designed to test the impact of reduced case loads. The aim of this study was to compare two levels of intensity of case management for patients with psychotic illnesses. Firstly to see if intensive case management reduces hospitalisation and costs. Secondly, to assess which levels of case management are appropriate for which levels of disability in terms of cost and outcome.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Schizophrenia and other psychoses
Intervention	Eligible patients were randomly allocated to standard case management (case loads 1:30-35) or intensive case management (case loads 1:10-15). 4 mental health centres in England, 3 in Inner London and 1 in Manchester.
Intervention type	Other
Primary outcome measure	Clinical symptoms and social functioning were measured at baseline, one years and two years. Hospital use was assessed at two years with subgroup analyses for Afro-Caribbean and the most disabled patients. A range of secondary outcomes based on clinical and social functioning was also assessed.
Secondary outcome measures	Not provided at time of registration
Overall study start date	30/09/1994
Completion date	30/07/1998

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	Both
Target number of participants	708
Key inclusion criteria	708 psychotic patients with histories of repeated hospital admission.
Key exclusion criteria	Does not match inclusion criteria
Date of first enrolment	30/09/1994
Date of final enrolment	30/07/1998

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

Department of Psychiatry

Manchester
M13 9WL
United Kingdom

Sponsor information

Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Government

The Department of Health
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Website	http://www.doh.gov.uk

Funders

Funder type

Government

NHS Mental Health National Research and Development Programme (UK)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	26/06/1999		Yes	No