Comparison of intensive and standard case management programmes for psychotic patients
| ISRCTN | ISRCTN15904286 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN15904286 |
| Protocol serial number | NMH10C GE179D |
| Sponsor | Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK) |
| Funder | NHS Mental Health National Research and Development Programme (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 20/11/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Francis Creed
Scientific
Scientific
Department of Psychiatry
Manchester Royal Infirmary
Oxford Road
Manchester
M13 9WL
United Kingdom
| Phone | +44 (0)161 276 5331 |
|---|---|
| Francis.Creed@man.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | UK700 study |
| Study objectives | Case management has increasingly been the recommended approach to care for the severely mentally ill as reliance on mental hospitals has diminished. An influential series of studies in the USA suggested that intensive case management, with case loads of 1:10-15, was particularly effective with the most severe patients, reducing hospitalisation and improving aspects of outcome. Despite equivocal results from replication studies in the UK and Europe this approach is becoming accepted policy. In this study we carried out a large multicentre investigation which was designed to test the impact of reduced case loads. The aim of this study was to compare two levels of intensity of case management for patients with psychotic illnesses. Firstly to see if intensive case management reduces hospitalisation and costs. Secondly, to assess which levels of case management are appropriate for which levels of disability in terms of cost and outcome. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Schizophrenia and other psychoses |
| Intervention | Eligible patients were randomly allocated to standard case management (case loads 1:30-35) or intensive case management (case loads 1:10-15). 4 mental health centres in England, 3 in Inner London and 1 in Manchester. |
| Intervention type | Other |
| Primary outcome measure(s) | Clinical symptoms and social functioning were measured at baseline, one years and two years. Hospital use was assessed at two years with subgroup analyses for Afro-Caribbean and the most disabled patients. A range of secondary outcomes based on clinical and social functioning was also assessed. |
| Key secondary outcome measure(s) | Not provided at time of registration |
| Completion date | 30/07/1998 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | All |
| Target sample size at registration | 708 |
| Key inclusion criteria | 708 psychotic patients with histories of repeated hospital admission. |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 30/09/1994 |
| Date of final enrolment | 30/07/1998 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Department of Psychiatry
Manchester
M13 9WL
United Kingdom
M13 9WL
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 26/06/1999 | Yes | No |
