Standard versus rapid initiation of anti-hypertensive therapy
| ISRCTN | ISRCTN16286916 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN16286916 |
| Protocol serial number | N0237101856 |
| Sponsor | Department of Health (UK) |
| Funder | St Helens and Knowsley Hospitals NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 16/09/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Shirley Hulme
Scientific
Scientific
Diabetes Centre
Whiston Hospital
Prescot
L35 5DR
United Kingdom
| Phone | +44 (0)151 426 1600 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial, open design |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The aim of the study is to evaluate the impact on blood pressure control, patient satisfaction and well being and adherence to medication of conventional gradual titration of anti-hypertensive treatment versus rapid introduction and dose escalation of four anti-hypertensive agents in subjects with diabetic nephropathy. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular: Hypertension |
| Intervention | Standard versus rapid initiation of anti-hypertensive therapy |
| Intervention type | Other |
| Primary outcome measure(s) |
1. Patient adherence to treatment |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/04/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 24 |
| Key inclusion criteria | 24 subjects recruited from new patients entering the nephropathy clinic |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/11/2001 |
| Date of final enrolment | 01/04/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Diabetes Centre
Prescot
L35 5DR
United Kingdom
L35 5DR
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
