Advance care planning in advanced cancer - can it be achieved? A patient preference trial of a care planning discussion
| ISRCTN | ISRCTN27270911 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN27270911 |
| Protocol serial number | N/A |
| Sponsor | University College London (UK) |
| Funder | Dimbleby Cancer Care (United Kingdom) |
- Submission date
- 08/01/2007
- Registration date
- 16/02/2007
- Last edited
- 29/03/2022
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Louise Jones
Scientific
Scientific
Marie Curie Palliative Care Research Unit
Royal Free and University College Medical School
Hampstead Campus
Rowland Hill Street
London
NW3 2PF
United Kingdom
| l.jones@medsch.ucl.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled patient preference trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | Advance care planning in advanced cancer - can it be achieved? A patient preference trial of a care planning discussion |
| Study objectives | 1. What is the acceptability and feasibility of a patient preference randomised controlled trial of an intervention to facilitate planning for end-of-life care? 2. Which outcomes are appropriate and measurable to assess the effectiveness of this intervention? |
| Ethics approval(s) | Royal Free Hospital and Medical School Local Research Ethics Committee. Approved on 17.08.06, ref 06/Q501/93 |
| Health condition(s) or problem(s) studied | Cancer |
| Intervention | The intervention will consist of a one-to-one discussion with a trained mediator using a checklist of topic domains. Discussions will take place usually in participants' homes and last no more than one hour. Participants will be offered up to two further sessions with the mediator, to take place at a time of their choice. Discussions will be audio-taped and transcribed to examine the range and development of topics covered, how these change with time, and to ensure that the advisor has covered each domain as appropriate. |
| Intervention type | Other |
| Primary outcome measure(s) |
Change in scores on visual analogue scales measuring ability to discuss end-of-life planning with primary and secondary care professionals and close persons/members of the family |
| Key secondary outcome measure(s) |
1. Completion of an advance directive |
| Completion date | 07/07/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Not Specified |
| Target sample size at registration | 100 |
| Total final enrolment | 77 |
| Key inclusion criteria | 1. Have completed a primary course of treatment and still have clinically detectable, progressive, active disease 2. Are considered by the referring health professional to be well enough to complete the advance care planning discussion 3. Are over 18 years of age 4. Are able to give informed consent 5. Do not have psychotic illness 6. Speak and understand English (able to complete the questionnaires/interview) |
| Key exclusion criteria | 1. Have not completed a primary course of treatment and still have clinically detectable, progressive, active disease 2. Are not considered by the referring health professional to be well enough to complete the advance care planning discussion 3. Are under 18 years of age 4. Are unable to give informed consent 5. Have psychotic illness 6. Do not speak and understand English (able to complete the questionnaires/interview) |
| Date of first enrolment | 15/01/2007 |
| Date of final enrolment | 07/07/2008 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Marie Curie Palliative Care Research Unit
London
NW3 2PF
United Kingdom
NW3 2PF
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan | Not provided at time of registration |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/03/2011 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
| Plain English results | 20/07/2011 | 29/03/2022 | No | Yes |
Editorial Notes
29/03/2022: The following changes have been made:
1. The Cancer Research UK lay results summary has been added.
2. The total final enrolment number has been added.
