INcidence of VENous Thromboembolism after acute stroke in China

ISRCTN	ISRCTN34425939
DOI	https://doi.org/10.1186/ISRCTN34425939
Secondary identifying numbers	INVENT-10

Submission date: 28/04/2007
Registration date: 06/06/2007
Last edited: 19/10/2021

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Wang Yongjun
Scientific

Tiantan Hospital
Beijing
100050
China

Phone	+86 (0)10 6701 3383
Email	zhg_doc@yahoo.com

Study information

Study design	Multicentre observational, prospective, nested case-control study.
Primary study design	Observational
Secondary study design	Case-control study
Study setting(s)	Hospital
Study type	Treatment
Scientific title	INcidence of VENous Thromboembolism after acute stroke in China
Study acronym	INVENT-China
Study objectives	1. Incidence of venous thromboembolism after acute stroke in China was lower than in western countries 2. Risk factors are different between Venous Thromboembolism (VTE) and non-VTE 3. Anticoagulation and neurological rehabilation can reduce the incidence
Ethics approval(s)	Approval received from the Tiantan Hospital Ethics Committee on the 29th November 2006 (ref: 7).
Health condition(s) or problem(s) studied	Venous thromboembolism
Intervention	Group A: stroke inpatients with Deep Venous Thrombosis (DVT) during follow up Group B: stroke inpatients without DVT during follow up DVT will be determined by complete-comprehensive ultrasound sonography two weeks (14 ± 3 days) after stroke onset. Possible risk factors will be compared between group A and group B, these will include: 1. stroke subtype 2. NIHSS 3. Medical history 4. Complications 5. High Density Lipoprotein (HDL) 6. Low Density Lipoprotein (LDL) 7. Triglycerides (TG)
Intervention type	Other
Primary outcome measure	Incidence of Deep Venous Thrombosis after acute stroke in China, measured at two weeks (14 ± 3 days) after stroke onset.
Secondary outcome measures	Predict model of VTE in acute stroke in China, measured at two weeks (14 ± 3 days) after stroke onset.
Overall study start date	08/05/2007
Completion date	08/10/2007

Eligibility

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex
Target number of participants	1882
Key inclusion criteria	1. Older than 18 2. Acute stroke patients within seven days 3. Identified by Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) 4. National Institutes of Health Stroke Scale (NIHSS) item-six more than one
Key exclusion criteria	1. Transient Ischaemic Attacks (TIAs) 2. Sub-Arachnoid Haemorrhage (SAH) 3. Tumour 4. Medical history of VTE
Date of first enrolment	08/05/2007
Date of final enrolment	08/10/2007

Locations

Countries of recruitment

China

Study participating centre

Tiantan Hospital

Beijing
100050
China

Sponsor information

Beijing Tiantan Hospital (China)
Hospital/treatment centre

c/o Professor Yongjun Wang
Affiliated Hospital of Capital Medical University
Beijing
100050
China

"ROR"	https://ror.org/003regz62

Funders

Funder type

Industry

Glaxosmithkline (China)
Government organisation / For-profit companies (industry)

Alternative name(s): GlaxoSmithKline plc., GSK plc., GlaxoSmithKline plc, GSK
Location: United Kingdom

Beijing Municiple Science and Technology Commission (China)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Editorial Notes

19/10/2021: Proactive update review. No publications found. Search options exhausted.