The effects of a colorectal cancer screening programme for average-risk older Chinese adults
| ISRCTN | ISRCTN39658070 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN39658070 |
| Secondary identifying numbers | 21.0205 |
- Submission date
- 04/08/2022
- Registration date
- 09/08/2022
- Last edited
- 05/12/2023
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Plain English summary of protocol
Background and study aims
Colorectal cancer screening can help early detection of cancer. Motivational interviewing could be a strategy to increase people's intention and action toward screening. This study aims to estimate the feasibility and acceptability of the intervention and the preliminary estimation of its effect on screening intention and uptake, knowledge and health beliefs of participants.
Who can participate?
People aged between 50-75 years old without a history of colorectal cancer
What does the study involve?
The intervention group receive a motivational interviewing session
What are the possible benefits and risks of participating?
The potential benefits are that the participants may be motivated and have higher self-efficacy to obtain colorectal cancer screening. There are no risks involved in participation.
Where is the study run from?
The Neighbourhood Advice-Action Council (NAAC) (Hong Kong)
When is the study starting and how long is it expected to run for?
November 2021 to March 2022
Who is funding the study?
Investigator-initiated and funded (Hong Kong)
Who is the main contact?
Dr Dorothy Chan (Hong Kong)
dorothycns@cuhk.edu.hk
Contact information
Principal Investigator
ELB 812, 8/F
Hong Kong (China)
852
Hong Kong
| Phone | +852 39438165 |
|---|---|
| dorothycns@cuhk.edu.hk |
Study information
| Study design | Exploratory pilot randomized controlled study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Community |
| Study type | Screening |
| Participant information sheet | Not available in web format, please use the contact details to request a participant information sheet |
| Scientific title | Effects of a motivation-based, technology-enhanced colorectal cancer screening programme for average-risk older Chinese adults: An exploratory study |
| Study objectives | Participants who receive motivational interview sessions and information about access to screening will have colorectal cancer screening uptake |
| Ethics approval(s) | Approved 27/10/2021, The Chinese University of Hong Kong Survey and Behavioral Research Ethics Committee (G/F, Basic Medical Science Building; telephone not available; email not available), ref: SBRE-21-0205 |
| Health condition(s) or problem(s) studied | Prevention of colorectal cancer |
| Intervention | Block randomisation with varying block sizes (6, 8,10 and 12) was used to optimise allocation concealment and maintain a good balance between groups throughout the subject recruitment period when eligible participants were randomly allocated into either the intervention group or the control group. The assignments to the intervention or control groups were sealed in opaque envelopes. The sequentially numbered, opaque, sealed envelopes were given to the participants in the sequence in which they enter the study. The intervention group participants receive two sessions of motivational interviewing during the first 2 weeks (once per week, 1 h each), either onsite or through a real-time online Zoom meeting. One week after completing the motivational interviewing sessions, the interventionist will send interactive messages or phone calls to review the screening status of the participants. Participants will be encouraged to undergo screening and be provided with appropriate logistical support regarding the screening workflow (e.g., registration for the electronic health record sharing system, navigating and scheduling appointments). The control group participants receive the usual care and a fact sheet about CRC prevention. |
| Intervention type | Behavioural |
| Primary outcome measure | Faecal occult blood testing (FOBT)-based colorectal cancer screening uptake measured by checking the original receipt of attendance at 3 months since recruitment |
| Secondary outcome measures | 1. Perceived barriers to screening measured using a questionnaire and after completion of the intervention 2. Perceived benefits of screening measured using a questionnaire and after completion of the intervention 3. Perceived self-efficacy of screening measured using a questionnaire and after completion of the intervention 4. Screening intention measured using a questionnaire and after completion of the intervention 5. Knowledge of colorectal cancer and screening measured using a questionnaire and after completion of the intervention |
| Overall study start date | 01/11/2021 |
| Completion date | 31/03/2022 |
Eligibility
| Participant type(s) | Healthy volunteer |
|---|---|
| Age group | Adult |
| Sex | Both |
| Target number of participants | 40 |
| Total final enrolment | 40 |
| Key inclusion criteria | 1. Age between 50 and 75 years old 2. No history of colorectal cancer and did not have a faecal immunochemical test (FIT) in the past 2 years or colonoscopy in the past 10 years |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 01/11/2021 |
| Date of final enrolment | 31/03/2022 |
Locations
Countries of recruitment
- Hong Kong
Study participating centre
Level 3
Community Recreation Building
Shan King Estate
Tuen Mun
852
Hong Kong
Sponsor information
University/education
Central Avenue
Shatin
None available
Hong Kong
| Phone | ++852 39437000 |
|---|---|
| dorothycns@cuhk.edu.hk | |
| Website | http://www.cuhk.edu.hk/english/index.html |
"ROR" |
https://ror.org/00t33hh48 |
Funders
Funder type
Other
No information available
Results and Publications
| Intention to publish date | 31/12/2022 |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not expected to be made available |
| Publication and dissemination plan | 1. Planned publication in a high-impact peer-reviewed journal 2. The results will be disseminated at conferences |
| IPD sharing plan | The datasets generated during and/or analysed during the current study are not expected to be made available without consent from participants |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | 12/10/2023 | 05/12/2023 | Yes | No |
Editorial Notes
05/12/2023: Publication reference added.
08/08/2022: Trial's existence confirmed by The Chinese University of Hong Kong Survey and Behavioral Research Ethics Committee.
