Contact information
Type
Scientific
Primary contact
Prof Gavin Perkins
ORCID ID
Contact details
Warwick Medical School Clinical Trials Unit
University of Warwick
Coventry
CV4 7AL
United Kingdom
-
g.d.perkins@warwick.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
PB-PG-1207-14246
Study information
Scientific title
Cardiopulmonary resuscitation (CPR) quality improvement programme: a multicentre, prospective, cohort study
Acronym
Study hypothesis
Implementing a CPR quality improvement initiative will improve the rate of return of spontaneous circulation and other outcomes in patients sustaining cardiac arrest
Ethics approval
Coventry Research Ethics Committee, 26/06/2009, REC ref: 09/H1210/65
Study design
Multicentre prospective cohort study
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Hospitals
Trial type
Treatment
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet.
Condition
In-hospital cardiac arrests
Intervention
1. Control
2. CPR feedback through Q-CPR® (Laerdal medical, UK)
3. CPR feedback through Q-CPR® (Laerdal medical, UK) plus team briefing / debriefing
Intervention type
Other
Phase
Not Applicable
Drug names
Primary outcome measure
Survived event [defined as sustained (> 20 minutes) return of spontaneous circulation]
Secondary outcome measures
1. Patient outcomes
1.1. Any return of spontaneous circulation
1.2. Survival to hospital discharge
1.3. Cerebral performance category of patients at discharge
2. Process outcomes
2.1. Quality of emergency calls
2.2. Chest compression depth, rate
2.3. No flow time
2.4. Duration of pre and post-shock pauses
2.5. Ventilation rate
2.6. time to first shock
2.7.Appropriate decision to shock
3. Team factors
3.1. CPR knowledge
3.2. Confidence / preparedness
Overall trial start date
01/11/2009
Overall trial end date
31/01/2013
Reason abandoned (if study stopped)
Eligibility
Participant inclusion criteria
Patients have to be either 18 or older and suffer an in-hospital cardiac arrest where resuscitation is attempted (defined as loss of a pulse requiring the delivery of chest compressions).
Participant type
Patient
Age group
Adult
Gender
Both
Target number of participants
912
Participant exclusion criteria
1. Patient has a Do-not-attempt resuscitation order written and documented in their medical records
2. Cardiac arrest not attended by a resuscitation team
3. Out - of - hospital cardiac arrest
4. Previous participation in this study
Recruitment start date
01/11/2009
Recruitment end date
31/01/2013
Locations
Countries of recruitment
United Kingdom
Trial participating centre
Warwick Medical School Clinical Trials Unit
Coventry
CV4 7AL
United Kingdom
Sponsor information
Organisation
Heart of England NHS Foundation Trust (UK)
Sponsor details
c/o Elizabeth Adey
R+D Manager
MIDRU
Bordesley Green East
Birmingham
B9 5SS
United Kingdom
-
Elizabeth.Adey@heartofengland.nhs.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (PB-PG-1207-14246)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Basic results (scientific)
Publication list
2011 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/22008636
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26186567
Publication citations
-
Protocol
Perkins GD, Davies RP, Quinton S, Woolley S, Gao F, Abella B, Stallard N, Cooke MW, , The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes: a cohort study: trial protocol., Scand J Trauma Resusc Emerg Med, 2011, 19, 58, doi: 10.1186/1757-7241-19-58.
-
Results
Couper K, Kimani PK, Abella BS, Chilwan M, Cooke MW, Davies RP, Field RA, Gao F, Quinton S, Stallard N, Woolley S, Perkins GD; Cardiopulmonary Resuscitation Quality Improvement Initiative Collaborators, The System-Wide Effect of Real-Time Audiovisual Feedback and Postevent Debriefing for In-Hospital Cardiac Arrest: The Cardiopulmonary Resuscitation Quality Improvement Initiative, Crit Care Med, 2015, 43, 11, 2321-2331, doi: 10.1097/CCM.0000000000001202.