Cardiopulmonary resuscitation (CPR) quality improvement programme

ISRCTN	ISRCTN56583860
DOI	https://doi.org/10.1186/ISRCTN56583860
Secondary identifying numbers	PB-PG-1207-14246

Submission date: 30/11/2010
Registration date: 05/07/2011
Last edited: 04/02/2016

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Gavin Perkins
Scientific

Warwick Medical School Clinical Trials Unit
University of Warwick
Coventry
CV4 7AL
United Kingdom

Email	g.d.perkins@warwick.ac.uk

Study information

Study design	Multicentre prospective cohort study
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Participant information sheet	Not available in web format, please use the contact details below to request a patient information sheet.
Scientific title	Cardiopulmonary resuscitation (CPR) quality improvement programme: a multicentre, prospective, cohort study
Study objectives	Implementing a CPR quality improvement initiative will improve the rate of return of spontaneous circulation and other outcomes in patients sustaining cardiac arrest
Ethics approval(s)	Coventry Research Ethics Committee, 26/06/2009, REC ref: 09/H1210/65
Health condition(s) or problem(s) studied	In-hospital cardiac arrests
Intervention	1. Control 2. CPR feedback through Q-CPR® (Laerdal medical, UK) 3. CPR feedback through Q-CPR® (Laerdal medical, UK) plus team briefing / debriefing
Intervention type	Other
Primary outcome measure	Survived event [defined as sustained (> 20 minutes) return of spontaneous circulation]
Secondary outcome measures	1. Patient outcomes 1.1. Any return of spontaneous circulation 1.2. Survival to hospital discharge 1.3. Cerebral performance category of patients at discharge 2. Process outcomes 2.1. Quality of emergency calls 2.2. Chest compression depth, rate 2.3. No flow time 2.4. Duration of pre and post-shock pauses 2.5. Ventilation rate 2.6. time to first shock 2.7.Appropriate decision to shock 3. Team factors 3.1. CPR knowledge 3.2. Confidence / preparedness
Overall study start date	01/11/2009
Completion date	31/01/2013

Eligibility

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	Both
Target number of participants	912
Key inclusion criteria	Patients have to be either 18 or older and suffer an in-hospital cardiac arrest where resuscitation is attempted (defined as loss of a pulse requiring the delivery of chest compressions).
Key exclusion criteria	1. Patient has a Do-not-attempt resuscitation order written and documented in their medical records 2. Cardiac arrest not attended by a resuscitation team 3. Out - of - hospital cardiac arrest 4. Previous participation in this study
Date of first enrolment	01/11/2009
Date of final enrolment	31/01/2013

Locations

Countries of recruitment

England
United Kingdom

Study participating centre

Warwick Medical School Clinical Trials Unit

Coventry
CV4 7AL
United Kingdom

Sponsor information

Heart of England NHS Foundation Trust (UK)
Hospital/treatment centre

c/o Elizabeth Adey
R+D Manager
MIDRU
Bordesley Green East
Birmingham
B9 5SS
England
United Kingdom

Email	Elizabeth.Adey@heartofengland.nhs.uk

Funders

Funder type

Government

National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (PB-PG-1207-14246)

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Protocol article	protocol	18/10/2011		Yes	No
Results article	results	01/11/2015		Yes	No

Editorial Notes

04/02/2016: Publication reference added.