Assessing the effectiveness of a lateral glide cervical spine mobilisation on cervicobrachial (neck and arm) pain

ISRCTN	ISRCTN62431186
DOI	https://doi.org/10.1186/ISRCTN62431186
Protocol serial number	09/H1203/45
Sponsor	University of Birmingham (UK)
Funder	Manipulation Association of Chartered Physiotherapists (UK)

Submission date: 16/06/2010
Registration date: 14/04/2011
Last edited: 04/10/2017

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Musculoskeletal Diseases

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Ms Emma Salt
Scientific

Physiotherapy Department
Queen's Hospital
Belvedere Road
Burton on Trent
DE13 0RB
United Kingdom

Email	EJS495@bham.ac.uk

Study information

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	A randomised controlled trial to assess the effectiveness of a lateral glide cervical spine mobilisation on cervicobrachial (neck and arm) pain
Study acronym	CBS Trial
Study objectives	The primary objective of this study is to investigate whether a self-management protocol with lateral glide mobilisation is more beneficial than a self-management protocol in isolation for participants with cervicobrachial syndrome (CBS).
Ethics approval(s)	South Staffordshire Local Research Ethics Committee approval pending as of 17/06/2010
Health condition(s) or problem(s) studied	Musculoskeletal pain
Intervention	Patients will be randomised to 1. Lateral glide with self-management 2. Self-management
Intervention type	Other
Primary outcome measure(s)	Pain, assessed by Visual Analogue Score (VAS)
Key secondary outcome measure(s)	1. Short Form 36-item Health Survey (SF36) (RAND) 2. Neck and Upper Limb Index (NULI) 3. Tampra scale of Kinesiophobia 4. Global Rating of Change (GROC) 5. Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) 6. Upper limb nerve extensability test 7. Cervical Active Range Of Motion (AROM)
Completion date	24/06/2012

Eligibility

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	96
Key inclusion criteria	1. Aged 18 - 65 years experiencing CBS (described as pain originating in the neck with associated pain radiating below the level of the shoulder joint into the arm) with or without parasthesia and or weakness in a dermatomal distribution 2. Had symptoms for greater than 6 weeks 3. Adequate knowledge of English to participate in a neuro-musculoskeletal examination and to answer the study questionnaire 4. Able to attend assessment and treatment appointments 5. Will have verbally agreed to attend the review appointment at 6, 26 and 52 weeks following initiation of the treatment
Key exclusion criteria	1. Presenting with any red flags: severe unremitting night pain, unexplained weight loss, history of cancer, general malaise, and constant unvarying pain 2. Bilateral arm symptoms 3. Signs and symptoms strongly suggestive of thoracic outlet syndrome or a specificperipheral pathology e.g. adhesive capsulitis, sub acromial impingement etc. 4. Specific pathology affecting nerve function e.g. multiple sclerosis, known peripheral vascular disease, diabetes 5. Known specific pathology affecting systemic joint function e.g. rheumatoid arthritis, ankylosing spondylitis 6. Cervical spine surgery, botulinum toxin injections or epidural injections to cervical spine or planned imminent treatment 7. Having other forms of manual therapy for their CBS symptoms e.g. osteopathy or chiropractics 8. Involved in compensation and or litigation associated with neck and or upper limb pain 9. Already involved in a research trial
Date of first enrolment	24/06/2009
Date of final enrolment	24/06/2012

Locations

Countries of recruitment

United Kingdom
England

Study participating centre

Queen's Hospital

Burton on Trent
DE13 0RB
United Kingdom

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

Editorial Notes

MW 04/10/2017: No publications found in PubMed, verifying study status with principal investigator.