Ontario Printed Educational Message trial (OPEM): changing physician decision making towards more evidence based choices

ISRCTN ISRCTN72772651
DOI https://doi.org/10.1186/ISRCTN72772651
Secondary identifying numbers MCT-67916
Submission date
21/07/2005
Registration date
21/07/2005
Last edited
14/12/2021
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English Summary

Not provided at time of registration

Contact information

Dr Merrick Flynn Zwarenstein
Scientific

Institute for Clinical Evaluative Sciences
2075 Bayview Ave
G106
Toronto, Ontario
M4N 3M5
Canada

Phone +1 (0)416 480 4055 ext. 7439
Email merrick.zwarenstein@ices.on.ca

Study information

Study designSingle-centre randomised cluster and factorial trial
Primary study designInterventional
Secondary study designCluster randomised trial
Study setting(s)GP practice
Study typeOther
Participant information sheet Not available in web format, please use contact details to request a participant information sheet
Scientific titlePrinted Educational Materials (PEMs) and their impact on physician decision making towards more evidence based choices: a single centre randomised tria
Study acronymOPEM
Study hypothesisPrinted Educational Materials (PEMs) will change physician decision making towards more evidence based choices.

Study Objective:
To measure the impact of PEMs on physician behaviour.

This description covers three replicates, independantly randomised. Each of the three sequential studies, aimed to asses the effects of printed educational materials on practice change by physicians. Each of the three replicates was aimed at a different condition and group of patients, and used different messages, but the same message formats.

These three seperate trials, essentially identical in design, tested the impact of printed educational messages aimed at:
1. Increasing coverage of retinal screening among all adult patients with diabetes
2. Intensification of cardiovascular treatment for patients over 65 years of age, with diabetes, and
3. At encouraging physicians to choose thiazides for initiation of hypertension therapy in their patients over 65 years, with newly diagnosed uncomplicated hypertension.
Ethics approval(s)Research Ethics Board of Sunnybrook & Women's College Health Science Centre, Toronto, Ontario (Canada), 29/04/2004, ref: #135-2004
ConditionDiabetes, hypertension
InterventionPosted printed educational materials (PEM) as follows:
Intervention arm 1 will receive 'informed' with an attached short outsert
Intervention arm 2 will receive 'informed' with an attached short outsert and longer insert
Intervention arm 3 will receive 'informed' with an attached long insert
Control arm will receive 'informed' only with no attachments
Intervention typeOther
Primary outcome measureThree trials:
1. Proportion of new hypertensives on diuretics
2. Proportion of diabetics who receive retinal screening
3. Proportion of diabetics who receive lipid lowering and antihypertensive medication and an ACE inhibitor

All measured from routinely collected health insurance and administrative information: OHRI, ODB, CIHI
Secondary outcome measuresNo secondary outcome measures
Overall study start date01/01/2005
Overall study end date01/07/2006

Eligibility

Participant type(s)Patient
Age groupAdult
SexBoth
Target number of participants5547
Participant inclusion criteria5547 actively practicing family (FP) and general practitioners (GP) in Ontario (~25 years and above, either sex) that have more than 100 patients over 65 years of age in fee for service practice with greater $50,000 billings to OHIP in 2003, randomised each time for three mail-outs of PEMs - the Printed Educational Materials
Participant exclusion criteriaPhysicians who have elected not to receive 'informed', a newsletter on evidence based practice out of the Institute for Clinical Evaluative Sciences (ICES)
Recruitment start date01/01/2005
Recruitment end date01/07/2006

Locations

Countries of recruitment

  • Canada

Study participating centre

Institute for Clinical Evaluative Sciences
Toronto, Ontario
M4N 3M5
Canada

Sponsor information

Institute for Clinical Evaluative Sciences - Toronto (Canada)
Research organisation

Room G1 06
2075 Bayview Avenue
Toronto
M4N 3M5
Canada

Email info@ices.on.ca
Website http://www.ices.on.ca/
ROR logo "ROR" https://ror.org/05p6rhy72

Funders

Funder type

Research organisation

Canadian Institutes of Health Research (CIHR) (Canada), ref: MCT-67916
Government organisation / National government
Alternative name(s)
Instituts de Recherche en Santé du Canada, Canadian Institutes of Health Research (CIHR), CIHR_IRSC, Canadian Institutes of Health Research | Ottawa ON, CIHR, IRSC
Location
Canada

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing planNot provided at time of registration

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Protocol article process evaluation protocol 26/11/2007 Yes No
Protocol article protocol 26/11/2007 Yes No
Protocol article sub-trial protocol 26/11/2007 Yes No
Results article diabetic retinopathy results 06/08/2014 Yes No
Results article diabetic retinopathy results 06/08/2014 Yes No
Results article hypertension results 13/09/2016 Yes No
Results article hypertension results 17/09/2016 Yes No
Results article 11/12/2021 14/12/2021 Yes No

Editorial Notes

14/12/2021: Publication reference added.
19/09/2016: Publication reference added.
14/09/2016: Publication reference added.