A comparison of patient satisfaction and complications following keyhole surgery wounds closed with tissue glue or stitches

ISRCTN	ISRCTN80786695
DOI	https://doi.org/10.1186/ISRCTN80786695
Protocol serial number	06/wmw01/55
Sponsor	Carmarthenshire NHS Trust (UK)
Funder	Carmarthenshire NHS Trust (UK) - Research and Development Office (now known as Hywel Dda NHS Trust)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Mr William Beasley
Scientific

Department of Gastrointestinal Surgery
Singleton Hospital
Abertawe Bro Morgannwg University NHS Trust
Sketty Lane
Swansea
SA2 8QA
United Kingdom

Primary study design	Interventional
Study design	Single blind randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Patient satisfaction and complications following laparoscopic wound closure with 2-octylcyanoacrylate or vicryl: a single blind randomised controlled trial
Study objectives	Closure of laparoscopic wounds with tissue adhesives is associated with higher patient satisfaction and lower complication rates than with conventional suturing.
Ethics approval(s)	Dyfed Powys Research Ethics Committee approved on the 3rd January 2007 (ref: 06/wmw01/55)
Health condition(s) or problem(s) studied	Laparoscopic general surgery
Intervention	Intervention: Laparoscopic wound closure with 2-cyanoacrylate tissue adhesive Control: Laparoscopic wound closure with subcuticular stitches Total follow up was six weeks.
Intervention type	Procedure/Surgery
Primary outcome measure(s)	Patient satisfaction in terms of wound appearance and wound closure technique. Measured at six weeks post-operatively.
Key secondary outcome measure(s)	1. Wound closure time, measured at the time of operation 2. Wound complications (dehisence, infection, resuturing), measured at six weeks post-operatively 3. Wound pain, measured at six weeks post-operatively 4. Antibiotic usage, measured at the time of operation 5. Unscheduled medical review, measured at six weeks post-operatively
Completion date	01/02/2009

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	300
Key inclusion criteria	1. All adults (aged 18 years and over), both males and females 2. Elective, general surgical, laparoscopic patients
Key exclusion criteria	1. Known 2-octylcyanoacrylate hypersensitivity 2. Conversion to open procedure
Date of first enrolment	01/02/2007
Date of final enrolment	01/02/2009

Department of Gastrointestinal Surgery

Swansea
SA2 8QA
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

20/05/2016: No publications found, verifying study status with principal investigator.