Pilot study of Cognitive Behaviour Therapy (CBT) versus usual treatment in those with Antisocial Personality Disorder (ASPD) with aggressive behaviour
| ISRCTN | ISRCTN89922377 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN89922377 |
| Protocol serial number | G0400922 ID: 71697 |
| Sponsor | Greater Glasgow NHS (UK) |
| Funder | Medical Research Council (MRC) (UK) (G0400922) |
- Submission date
- 16/08/2005
- Registration date
- 07/10/2005
- Last edited
- 20/08/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Kate Davidson
Scientific
Scientific
Psychological Medicine
Gartnavel Royal Hospital
1055 Great Western Road
Glasgow
G12 0XH
United Kingdom
| Phone | +44 (0)141 211 3908/3900 |
|---|---|
| k.davidson@clinmed.gla.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | ASCOT |
| Study objectives | This pilot study has four specific and related aims. 1. Development of treatment 2. Chart treatment as usual 3. Test out standardised measures and different modes of delivery if levels of literacy are found to be poor 4. Determine a preliminary efficacy estimate for CBT in this group |
| Ethics approval(s) | Added as of 13/08/2007: 1. Ethics Board for lead site: NHS Greater Glasgow Primary Care Trust (Community and Mental Health), approved on 16/05/2005 (ref: 05/S0701/46) Other sites: 2. St Mary's Research Ethics Committee, approved on 10/06/2005 3. Ealing and West London Mental Health Trust (WLMHT) Local Research Ethics Committee, approved on 17/11/2005 |
| Health condition(s) or problem(s) studied | Antisocial Personality Disorder |
| Intervention | Cognitive behaviour therapy versus usual treatment |
| Intervention type | Other |
| Primary outcome measure(s) |
Aggression & offending behaviour |
| Key secondary outcome measure(s) |
1. Social functioning |
| Completion date | 12/09/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | All |
| Target sample size at registration | 56 |
| Key inclusion criteria | 1. A diagnosis of ASPD with aggressive behaviour 2. Aged 18 or above 3. Affirmation of any item on the Amended MacArthur Community Violence Screening Instrument (MCVSI)* interview (*3 months prior to baseline) |
| Key exclusion criteria | 1. Those who are currently receiving inpatient treatment for a mental state disorder 2. Those currently receiving a systematic psychological therapy 3. Those who have insufficient knowledge of English to enable them to be assessed adequately and to understand the treatment approach |
| Date of first enrolment | 13/09/2005 |
| Date of final enrolment | 12/09/2007 |
Locations
Countries of recruitment
- United Kingdom
- Scotland
Study participating centre
Psychological Medicine
Glasgow
G12 0XH
United Kingdom
G12 0XH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/04/2009 | Yes | No |
