A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer
| ISRCTN | ISRCTN92341395 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN92341395 |
| Protocol serial number | CRBT |
| Sponsor | Leicester General Hospital (UK) |
| Funder | Leicester General Hospital (UK) |
- Submission date
- 19/08/2002
- Registration date
- 19/08/2002
- Last edited
- 15/10/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr
Scientific
Scientific
UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Colorectal cancer |
| Intervention | 1. Arm A: Surgery without transfusion 2. Arm B: Surgery with standard blood transfusion 3. Arm C: Surgery with leucodepleted blood transfusion |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 31/12/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | 1. Patients undergoing elective resection of colorectal carcinoma 2. No transfusion of blood in the 6 months preceding the operation 3. No transfusion of blood prior to the first postoperative sample 4. No concurrent immunosuppressive medication 5. No previous transfusion reaction requiring cessation of transfusion |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2000 |
| Date of final enrolment | 31/12/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom
NW1 2DA
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
